Cancer and Sagittarius can be the most compatible friends if they respect each other's decisions and needs. For example, Cancerians must say yes to Sagittarius’s adventure choices, while Sagittarians also need to agree to cancerians' decisions to not be over-excited about the little things and must think about them before making any final decision. In friendship, Sagittarius and Cancers can also support each other’s growth and appreciate each other’s strengths. Both these zodiac signs can also offer each other new perspectives and experiences.